Build the Future of Obesity and Weight Management

Our Commitment

Obesity and overweight is estimated to affect more than 2.5 billion adults worldwide, almost 60% of whom are living with at least one co-occurring metabolic, heart, liver, or kidney disease. Despite growing consensus that obesity is a chronic, multifactorial disease, millions of people remain undiagnosed until serious health complications emerge. 

At AstraZeneca, our mission is to advance research into the next generation of targeted obesity and weight management solutions to deliver not only effective weight loss but also durable long-term weight management solutions for people living with obesity and overweight. This approach has the potential to substantially reduce disease burden and improve health outcomes for patients.

A New Era of Innovation

It’s an exciting time within Obesity and Weight Management - an area where the science is quickly evolving and highlighting new pathways and mechanisms that show promise in helping patients to manage their excess weight. In recent years, we’ve seen a new wave of innovation that has improved options for many, but this is coupled with a significant current and growing patient need, with the World Health Organization (WHO) recognising it as one of the most critical public health challenges today and in the future.

AstraZeneca is investing in cutting-edge science to tackle the metabolic, inflammatory, fibrotic, and genetic drivers. Through precision medicine, we aim to develop targeted, personalised therapies that could halt disease progression and prevent cirrhosis or cancer. Our goal is to deliver next-generation therapeutics with unique benefits for people living with this disease of unmet urgent need. Our continued research and innovation focus is on deepening our understanding of the root causes of obesity and overweight, recognising the individual patient needs, preferences, and underlying risk factors to develop next-generation treatments that deliver meaningful full-body health benefits.

Why Join Us?

Our BioPharmaceuticals pipeline is rapidly expanding, and it takes something special to deliver next-generation Obesity and Weight Management solutions to patients and healthcare professionals. Here, you’ll be a challenger, rethinking how we approach unmet needs and acting with purpose. By harnessing science and technology, you’ll help create innovations that truly impact lives. At AstraZeneca, every decision is centred around serving patients, and you’ll be empowered to go above and beyond, collaborating with trusted partners to shape the future of care. In our supportive and dynamic environment, your ideas are valued, diverse perspectives drive progress, and continuous learning helps you build your career. Join us and grow as part of a winning, global team, making a real difference for people living with Obesity and Weight Management.

Join us to shape markets, build strategies with real‑world impact, and grow your career where bold ambition meets patient‑centered innovation.